Parkinson's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Parkinson's Disease, including details on symptoms, treatment, genetics, medication. | ||||||
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Impaired driving from medical conditions: a 70-year-old man trying to decide if he should continue driving.Rizzo M Division of Neuroergonomics, and Department of Neurology, University of Iowa, Iowa City, IA 52242-1053, USA. matthew-rizzo@uiowa.edu Some medical disorders can impair performance, increasing the risk of driving safety errors that can lead to vehicle crashes. The causal pathway often involves a concatenation of factors or events, some of which can be prevented or controlled. Effective interventions can operate before, during, or after a crash occurs at the levels of driver capacity, vehicle and road design, and public policy. A variety of systemic, neurological, psychiatric, and developmental disorders put drivers at potential increased risk of a car crash in the short or long term. Medical diagnosis and age alone are usually insufficient criteria for determining fitness to drive. Strategies are needed for determining what types and levels of reduced function provide a threshold for disqualification in drivers with medical disorders. Evidence of decreased mileage, self-restriction to driving in certain situations, collisions, moving violations, aggressive driving, sleepiness, alcohol abuse, metabolic disorders, and multiple medications may trigger considerations of driver safety. A general framework for evaluating driver fitness relies on a functional evaluation of multiple domains (cognitive, motor, perceptual, and psychiatric) that are important for safe driving and can be applied across many disorders, including conditions that have rarely been studied with respect to driving, and in patients with multiple conditions and medications. Neurocognitive tests, driving simulation, and road tests provide complementary sources of evidence to evaluate driver safety. No single test is sufficient to determine who should drive and who should not. Published 9 March 2011 in JAMA, 305(10): 1018-26. Articles on Parkinson's Disease published 9 March 2011: Impaired driving from medical conditions: a 70-year-old man trying to decide if he should continue driving. JAMA, 305(10): 1018-26. Some medical disorders can impair performance, increasing the risk of driving safety errors that can lead to vehicle crashes. The causal pathway often involves a concatenation of factors or events, some of which can be prevented or controlled. Effective interventions can operate before, during, or after a crash occurs at the levels of driver capacity, vehicle and road design, and public policy. A variety of systemic, neurological, psychiatric, and developmental disorders put drivers at ... [Abstract] [Full-text] Impaired driving from medical conditions: a 70-year-old man trying to decide if he should continue driving. JAMA, 305(10): 1018-26. Some medical disorders can impair performance, increasing the risk of driving safety errors that can lead to vehicle crashes. The causal pathway often involves a concatenation of factors or events, some of which can be prevented or controlled. Effective interventions can operate before, during, or after a crash occurs at the levels of driver capacity, vehicle and road design, and public policy. A variety of systemic, neurological, psychiatric, and developmental disorders put drivers at ... [Abstract] [Full-text] Articles on Parkinson's Disease published 21 February 2011: Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet, 377(9766): 641-9. Articles on Parkinson's Disease published 24 January 2011: Neurophysiological evaluation of motor corticospinal pathways by TMS in idiopathic early-onset Parkinson's disease. Clin Neurophysiol, 122(3): 546-9. Contextual processing deficits in Parkinson's disease: the role of the frontostriatal system. Clin Neurophysiol, 122(3): 539-45. Neurophysiological evaluation of motor corticospinal pathways by TMS in idiopathic early-onset Parkinson's disease. Clin Neurophysiol, 122(3): 546-9. Contextual processing deficits in Parkinson's disease: the role of the frontostriatal system. Clin Neurophysiol, 122(3): 539-45. Articles on Parkinson's Disease published 18 January 2011: Segmental conformational disorder and dynamics in the intrinsically disordered protein α-synuclein and its chain length dependence. J Mol Biol, 405(5): 1267-83. Conformational ensembles of fully disordered natural polypeptides represent the starting point of protein refolding initiated by transfer to folding conditions. Thus, understanding the transient properties and dimensions of such peptides under folding conditions is a necessary step in the understanding of their subsequent folding behavior. Such ensembles can also undergo alternative folding and form amyloid structures, which are involved in many neurological degenerative diseases. Here, we ... [Abstract] [Full-text] © 2004-2011 Parkinson's Disease Research Today. All Rights Reserved. |
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