Parkinson's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Parkinson's Disease, including details on symptoms, treatment, genetics, medication.

Studying neurosurgical implants for Parkinson disease: a question of design.

Prehn AW, Vawter DE, Gervais KG, DeVries RG, Garrett JE, Freeman TB, McIndoo TQ

Minnesota Center for Health Care Ethics, 601 25th Avenue South, Minneapolis, MN 55454, USA. prehn@stolaf.edu

North American researchers' perspectives on designing neurosurgical implant studies for Parkinson disease (PD) challenged the custom of holding surgical trials to less stringent evidentiary standards than other clinical studies. Researchers supported placebo surgery-controlled trials. The framework they used to design and evaluate studies both of deep brain stimulation and cellular implants for PD may be applicable to a broad range of surgical implants for other disorders.

Published 24 October 2006 in Neurology, 67(8): 1503-5.
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