Parkinson's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Parkinson's Disease, including details on symptoms, treatment, genetics, medication.

Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: a case-control study.

Bower JH, Maraganore DM, Peterson BJ, Ahlskog JE, Rocca WA

Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. bower.james@mayo.edu

The authors studied the association of markers of inflammation with the later development of Parkinson disease (PD) using a case-control design (196 cases and 196 matched controls). The frequency of diseases of immediate-type hypersensitivity was significantly higher in cases than controls. In addition, cases used anti-inflammatory agents less frequently than controls (nonsignificant trend). The results may support the hypothesis that there is an inflammatory component in the pathogenesis of PD.

Published 8 August 2006 in Neurology, 67(3): 494-6.
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