Parkinson's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Parkinson's Disease, including details on symptoms, treatment, genetics, medication.

Atypical antipsychotics in the elderly with Parkinson disease and the "black box" warning.

Friedman JH

NeuroHealth Parkinson's Disease and Movement Disorders Center, 227 Centerville Rd., Warwick, RI 02886, USA. Joseph_Friedman@Brown.edu

In the last 2 years, regulatory agencies in the UK and the USA have made recommendations and "black box" warnings, regarding the use of atypical antipsychotic drugs in the elderly because of a purported increase in risk of stroke and death in elderly demented patients. These advisories did not address the adverse effects of "typical" (first-generation) antipsychotics. In this article, the author reviews the history of these developments and raises issues that still need to be addressed by the neurologic community.

Published 22 August 2006 in Neurology, 67(4): 564-6.
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