Parkinson's Disease Research - Symptoms, Treatment, Genetics, Medication

Parkinson's Disease Research Today is a free monthly online journal that collates and summarizes the latest research about Parkinson's Disease, including details on symptoms, treatment, genetics, medication.


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A case of levodopa-responsive camptocormia associated with advanced Parkinson's disease.

Ho B, Prakash R, Morgan JC, Sethi KD

Tufts-New England Medical Center Department of Neurology, USA.

BACKGROUND: A 48-year-old man with a 9-year history of Parkinson's disease who had previously shown a good response to levodopa presented for evaluation of increasingly disabling motor fluctuations and marked camptocormia. INVESTIGATIONS: Video-recorded neurological examinations when in 'off' and 'on' states, brain MRI scan. DIAGNOSIS: Advanced Parkinson's disease complicated by levodopa-responsive camptocormia. MANAGEMENT: Adjustment of dopaminergic therapy (carbidopa-levodopa and entacapone) to minimize motor fluctuations and camptocormia.

Published 6 September 2007 in Nat Clin Pract Neurol, 3(9): 526-30.
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